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    Rabbit Anti-CD5 antibody (bs-1113R)
    ~~~促銷,代碼KT22301~~~
    ~~~促銷,代碼KT22302~~~
    訂購熱線:400-901-9800
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    說明書: 50ul  100ul  200ul
    50ul/1138.00元
    100ul/1880.00元
    200ul/2900.00元
    大包裝/詢價
    產品編號 bs-1113R
    英文名稱 CD5
    中文名稱 CD5抗體
    別    名 T-cell surface glycoprotein CD5; Lymphocyte antigen 1; Ly-1; Lyt-1; CD5 antigen; CD 5; CD5 molecule; CD5 antigen (p56 62); CD5_HUMAN; LEU 1; LEU1; Ly12; LyA; Lymphocyte Antigen CD5; Lymphocyte antigen T1/Leu 1; Lymphocyte antigen T1/Leu-1; Lymphocyte glycoprotein T1/Leu1; OTTHUMP00000236973; p56 62; T1.  
    Specific References  (1)     |     bs-1113R has been referenced in 1 publications.
    [IF=1.42] Karaboga, ?hsan, Selim Demirtas, and Turan Karaca. "Investigation of the relationship between the Th17/IL-23 pathway and innate-adaptive immune system in TNBS-induced colitis in rats." Iranian Journal of Basic Medical Sciences 20.8 (2017): 870-879.  IHC-P ;  Rat.  
    研究領域 免疫學  干細胞  細胞表面分子  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用 WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 55kDa
    檢測分子量 67kDa
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CD5: 401-495/495 <Cytoplasmic>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

    Function:
    May act as a receptor in regulating T-cell proliferation.

    Subunit:
    Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1.

    Subcellular Location:
    Cell membrane; Single-pass type I membrane protein.

    Post-translational modifications:
    Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.

    Similarity:
    Contains 3 SRCR domains.

    SWISS:
    P06127

    Gene ID:
    921

    Database links:

    Entrez Gene: 921 Human

    Omim: 153340 Human

    SwissProt: P06127 Human

    Unigene: 58685 Human




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