CD307a;
Fc receptor homolog 1;
Fc receptor like protein 1;
Fc receptor-like protein 1;
FcR like protein 1;
FcR-like protein 1;
FCRH 1;
FcRH1;
FCRL 1;
FcRL1;
FCRL1_HUMAN;
hIFGP 1;
hIFGP1;
IFGP 1;
IFGP family protein 1;
IFGP1;
Immune receptor translocation associated protein 5;
Immune receptor translocation-associated protein 5;
immunoglobulin superfamily Fc receptor, gp42;
IRTA 5;
IRTA5;
RP11 367J7.7.
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量
45kDa
細胞定位
細胞膜
性 狀
Liquid
濃 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human FCRL1: 251-350/429 <Extracellular>
亞 型
IgG
純化方法
affinity purified by Protein A
緩 沖 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Function: May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.
Subcellular Location: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity: Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level).
Post-translational modifications: Phosphorylated on tyrosines upon activation.