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    Rabbit Anti-FCRL1 antibody (bs-16064R)
    ~~~促銷,代碼KT22301~~~
    ~~~促銷,代碼KT22302~~~
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說明書: 50ul  100ul  200ul
    50ul/1138.00元
    100ul/1880.00元
    200ul/2900.00元
    大包裝/詢價
    產品編號 bs-16064R
    英文名稱 FCRL1
    中文名稱 CD307a抗體
    別    名 CD307a; Fc receptor homolog 1; Fc receptor like protein 1; Fc receptor-like protein 1; FcR like protein 1; FcR-like protein 1; FCRH 1; FcRH1; FCRL 1; FcRL1; FCRL1_HUMAN; hIFGP 1; hIFGP1; IFGP 1; IFGP family protein 1; IFGP1; Immune receptor translocation associated protein 5; Immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA 5; IRTA5; RP11 367J7.7.  
    研究領域 細胞生物  免疫學  細胞膜受體  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, )
    產品應用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 45kDa
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human FCRL1: 251-350/429 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

    Function:
    May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.

    Subcellular Location:
    Cell membrane; Single-pass type I membrane protein.

    Tissue Specificity:
    Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level).

    Post-translational modifications:
    Phosphorylated on tyrosines upon activation.

    Similarity:
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

    SWISS:
    Q96LA6

    Gene ID:
    115350

    Database links:

    Entrez Gene: 115350 Human

    Omim: 606508 Human

    SwissProt: Q96LA6 Human

    Unigene: 656112 Human



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