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    Rabbit Anti-CD72/Cy5.5 Conjugated antibody (bs-2517R-Cy5.5)
    ~~~促銷,代碼SQ220725~~~
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-2517R-Cy5.5
    英文名稱 Anti-CD72/Cy5.5
    中文名稱 Cy5.5標記的CD72蛋白抗體
    別    名 B-cell differentiation antigen CD72; CD72b; LYB2; B cell differentiation antigen CD72; CD72 antigen; CD72 molecule; CD72c; Ly-19; Ly-32; Ly-m19; Lyb-2; Lyb2; LYB2, mouse, homolog of; Lymphocyte antigen 32; MGC108873; CD72_HUMAN.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 腫瘤  免疫學  干細胞  細胞表面分子  糖蛋白  細胞類型標志物  b-淋巴細胞  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, )
    產品應用 Flow-Cyt=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 40kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CD72 N-terminus
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface molecules such as the asialoglycoprotein receptors, CD23 and the Kupffer cell receptor. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.

    Function:
    Plays a role in B-cell proliferation and differentiation.

    Subunit:
    Homodimer; disulfide-linked. Associates with CD5. Interacts (tyrosine phosphorylated) with PTPN6/SHP-1 (By similarity).

    Subcellular Location:
    Membrane; Single-pass type II membrane protein.

    Tissue Specificity:
    Pre-B-cells and B-cells but not terminally differentiated plasma cells.

    Post-translational modifications:
    Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity).

    Similarity:
    Contains 1 C-type lectin domain.

    Database links:

    Entrez Gene: 971 Human

    Omim: 107272 Human

    SwissProt: P21854 Human

    Unigene: 116481 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    CD72是一個重要的B細胞特異性受體。屬于II型膜內糖蛋白成員中的細胞表面分子非唾液酸糖蛋白受體,雖然其分子功能目前還不清楚,但目前發現CD72的多態性與多種腫瘤有關。
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